TG and B-cell chronic lymphocytic leukemia: Although some mouse CLL clones may have longer HCDR3 than normal B cells, as it has been shown in sets of UM-CLL in humans (5, 42), a comparison of the HCDR3 average length of the Traf2DNxBCL2-tg+/+ UM-CLL/SLL clones and those from the Eμ-TCL-1-tg, the MDR−/−, the miR-15a/16-1−/− and the IgH-TEμ-tg mice showed no significant differences among them and, in all cases, it was similar to the HCDR3 average length of normal mouse B cells.