TG and B-cell chronic lymphocytic leukemia: In addition, the comparison of B cell clones isolated from Traf2DNxBCL2-tg mice with all possible transgene combinations reveal a more restricted set of IGHV subgroup and IGHV gene usage by the expanded Traf2DNxBCL2-tg+/+ CLL/SLL clones compared to B cells from mice of the other genotypes.