Our results demonstrated an increase in the IL-6 secretion by BeWo cells in response to T. gondii infection, as previously reported (Castro et al., 2013; Barbosa et al., 2014, 2015), and the HO-1 induction by hemin treatment also enhanced the release of this cytokine, regardless of infection, as observed in myeloma cells (Wu et al., 2016). This evidence concerns the gene HMOX1 and infection.