Thus, in order to investigate whether T. gondii infection could interfere in the p38 MAPK activation in BeWo trophoblast cells and whether the HO-1 induction could be related with p38 MAPK activation in these cells, under parasite infection, we performed western blotting to detect and measure the expression of phosphorylated p38 MAPK (p-p38 MAPK). This evidence concerns the gene HMOX1 and parasitic infectious disease.