HMOX1 and plasma cell myeloma: Our results demonstrated an increase in the IL-6 secretion by BeWo cells in response to T. gondii infection, as previously reported (Castro et al., 2013; Barbosa et al., 2014, 2015), and the HO-1 induction by hemin treatment also enhanced the release of this cytokine, regardless of infection, as observed in myeloma cells (Wu et al., 2016).