HMOX1 and infection: Previously, our group investigated the role of HO-1 in T. gondii experimental infection in vivo, and we showed that the HO-1 activity was involved in the control of T. gondii replication in the lung of resistant BALB/c mice, and also in this organ and in the small intestine of susceptible C57BL/6 mice (Araujo et al., 2013).