GRIN1 and schizophrenia: In animal models, GluN1 ablation in GABAergic interneurons at the prenatal period can elicit a hypodopaminergic state in the cortex and a hyperdopaminergic state in the mesolimbic pathway, which is consistent with the dopamine disorder in schizophrenia (Field et al., 2011; Nakazawa et al., 2017).