It was speculated that redox state and NMDAR activity interacted with each other in schizophrenia (Hardingham and Do, 2016) and these two individual factors both had developmental effects on parvalbumin-expressing GABAergic interneurons in schizophrenia (Korotkova et al., 2010; Hasam-Henderson et al., 2018). The gene discussed is PVALB; the disease is schizophrenia.