As shown in Table 4, subsequent univariate analyses revealed that liver fibrosis stage at SVR 24 (F0-2 vs. 3–4, P < 0.001), platelet count at SVR24 (P = 0.004), history of hypertension (P = 0.006), AST level at SVR24 (P = 0.003), γGTP level at SVR24 (P = 0.019), FIB-4 index at SVR24 (P < 0.001), and post-treatment Ang2 level (P = 0.001) were significantly associated with non-regression of liver fibrosis stage between SVR24 and SVR96. Here, ANGPT2 is linked to Hepatic fibrosis.