Interestingly, GLUD1 expression was significantly decreased in GBM compared to AGII (p < 0.005 Dunn test), and its expression level presented discriminatory power to distinguish between GBM and NN (ROC AUC = 0.770; 95% CI, 0.128–0.332) and between GBM and AGII (ROC AUC = 0.742; 95% CI, 0.147–0.368) (Fig. 2). This evidence concerns the gene GLUD1 and glioblastoma.