Among the 51 loci associated with CAD, 13 were novel loci, 10 of which were mapped to protein-coding genes (i.e., HNRNPUL1, NAA25, FES, TNS1, CYP46A1, ABCG8, IGF2BP1, BCAS3, SMG6, APOE) (Table S4). The gene discussed is SMG6; the disease is coronary artery disorder.