MAPK3 and hepatocellular carcinoma: Angptl1 inhibits vascular endothelial growth factor and basic fibroblast growth factor-induced proliferation of the endothelial cells and exerts the anti-apoptotic action through an induction of phosphorylation of extracellular-signal-regulated kinase 1/2 (ERK1/2) and protein kinase Bα in hepatocellular carcinoma [8].