Among 204 target genes, DVL3: P = 6.98E-04, PPP2R2D: P = 1.53E-03, THSD4: P = 2.28E-12, CREB1: P = 3.12E-01, SYT7: P = 1.28E-48, and PRKACA: P = 5.68E-02 were markedly relationship with worse prognosis in cases with BC. The gene discussed is DVL3; the disease is breast cancer.