We performed 1:1 propensity score matching using R to evaluate the significance of newly reported parameters such as RETzPSA, EPHPSA, PSAD, PZPSAD, and ETzD when there were no differences in age, underlying diseases (diabetes mellitus and hypertension), and serologic test (Hb, albumin, serum ALP levels and PSA levels) between the two groups. The gene discussed is KLK3; the disease is Hypertension.