A PANTHER Pathways overrepresentation analysis revealed the Wnt signaling, Inflammation mediated by chemokine and cytokine signaling, Huntington disease, Alzheimer disease-presenilin, Cadherin signaling, Nicotinic acetylcholine receptor signaling, and Cytoskeletal regulation by Rho GTPase pathways to be significantly overrepresented by proteins up-regulated in vtg1-KO eggs (Fig. 4a). The gene discussed is CDH17; the disease is juvenile Huntington disease.