Similarly, the distributions of survival status also indicated that the survival rate and time of HCC high-risk group are significantly lower than the low-risk group (Fig. 3d, e), and the expression of 6 unfavorable prognostic factors (PRRT3-AS1, RP11-479G22.8, RP11-73M18.8, LINC01138, CTD-2510F5.4, and RP11-324I22.4) is increased with the risk score increases; on the contrary, the expression of beneficial prognostic factor (CTC-297N7.9) is decreased (Fig. 3c). The gene discussed is PRRT3; the disease is hepatocellular carcinoma.