Furthermore, the uptake in MC38-hPD-L1 tumor was rapid and high (6.24± 0.26 % ID/g), and the content of uptake in MC38-hPD-L1/KO tumor was 2.81± 0.52 %ID/g, but that in MC38 KO tumor was only 0.68±0.17 %ID/g. This evidence concerns the gene CD274 and neoplasm.