IGHE and Allergy: Due to the deleterious consequences of the false penicillin allergy label, all patients with a history compatible with an IgE-mediated reaction should be candidates for skin tests.(2)In the absence of a clinical history, skin tests should not be used as a screening method.(2)Patients with a family history of BL allergy, with no past history of reaction, do not need to be evaluated and can be given BL safely.(2)