We found that the mRNA expression of IFN-β and IL-6, which are vital antiviral modulators of innate immune response [1,3], significantly increased in DDX5-knockdown MEFs at 6 and 12 h post-infection (hpi) with VSV (Figs S1A, 1A, 1E, and S1 Table). The gene discussed is IFNB1; the disease is infection.