There are 12 tumor cell lines (A549/ATCC-Lung, CCRF-CEM-Leukemia, HCC-2998-Colon, HCT-116-Colon, HCT-15-Colon, HOP-62-Lung, NCI-H23-Lung, NCI-H460-Lung, OVCAR-5-Ovarian, RPMI-8226-Leukemia, SK-OV-3-Ovarian and SW-620-Colon) harboring defective KRAS, with significant chemosensitive SOMDTP nodes appearing in meta-clades 21, 22 and 27. This evidence concerns the gene KRAS and neoplasm.