On the other hand, when we integrated the gene expression levels of the NKG2DL family collected from the GEPIA website and the TCGA database in COAD patient tumor tissues and normal tissues, the results also found that the expression levels of MICB, ULBP1, ULBP2, ULBP3, RAET1E, RAET1G and RAET1L (except MICA) were consistent. This evidence concerns the gene MICA and neoplasm.