ULBP2 and colon adenocarcinoma: First, based on the TCGA cohort, we performed prognostic survival analysis of the NKG2DL genes in COAD, the multivariate analyses showed that the high expression of ULBP2 [adjusted P = 0.007, HR (95% CI) = 2.490 (1.349–6.405)] and RAET1E [adjusted P = 0.009, HR (95% CI) = 0.236 (0.157–0.764)] were correlated with the prognosis of COAD RFS.