The expression data of NKG2DL genes in tumor tissues from COAD patients and normal tissues were downloaded from the GEPIA website and showed that the MICA gene was lowly expressed in COAD tumor tissues, while MICB, ULBP1, ULBP2, ULBP3, RAET1E, RAET1G, and RAET1L were highly expressed in COAD tumor tissues (Supplementary Figure 4). Here, ULBP2 is linked to colon adenocarcinoma.