Due to the high prevalence of obesity and T2D among Chileans and the heterogenic effect of the haplotype on T2D in different Hispanic groups, we studied the association of SLC16A11 with adiposity and metabolic markers, using the rs75493593 SNP as a proxy for the 5 SNP haplotype in healthy Chilean adults. Here, SLC16A11 is linked to type 2 diabetes mellitus.