Importantly, this study showed that the expression of miR-150 and miR-151 was decreased due to the BCR-ABL expression; however, down-regulation of miR-10a was independent on BCR-ABL1 activity and in turn caused increasing cell growth of CML cells by stimulating upstream stimulatory factor 2 (USF2) (Agirre et al., 2008[1]). The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.