The expression of 16 genes among 27 genes was found to be significantly related to clinical results; the lower expression of ACLY, LSM4, PITX2, TXNRD1, POLD3, GINS2, FGF13, E2F2 and higher expression of ALDH1L2, CYP7A1, QDPR, TXNIIP, PPAP2A, PIK3R3, H2BFXP, CLYBL genes were found to have significant effects on liver cancer patient life spans as shown by the Kaplan–Meier plots (Figure 6). The gene discussed is POLD3; the disease is liver cancer.