They were also involved in eQTLs and ct-eQTLs that showed different patterns of association in cases versus controls (i.e., CR1, HLA-DRB1, HLA-DRB5, and ECHD3) or differentially expressed in AD cases versus controls (i.e., WWOX and LRRC2). The gene discussed is HLA-DRB1; the disease is Alzheimer disease.