The hotspot mutation of SLC26A4 was c.919–2A > G, with an allele frequency of 0.49%, followed by c.919-18T > G, with an allele frequency of 0.45%, which is slightly lower than the findings in Zhao's report.[30]SLC26A4 governs Pendred syndrome, which is one of the most common forms of syndromic hearing Loss. Here, SLC26A4 is linked to hearing loss disorder.