In addition, our ROC curve analysis results identified that age, AMH, and ORPI were significant variables of subjects and controls for evaluating ovarian reserve, the cut-off value of age was similar to the above-mentioned report.[19] However, we found that FSH, FSH/LH ratio, and TT were more easily changed by influential factors, particularly in infertile patients. Here, PLOD1 is linked to Infertility.