AMH and Infertility: Data have further revealed that AFC, AMH level, along with median and mean AMH levels, decrease steadily and gradually with increasing age,[14–16] thus reflecting a decline of the non-growing follicle pool.[1] Furthermore, the age-specific reduction of the ovarian reserve was similar in both infertile and fertile female patients; serum AMH concentration decreased by 6% or 6.2%, and AFC declined by 4.5% per year with increased age.