SH3PXD2B and hepatocellular carcinoma: To explore the relationship between SH3PXD2B expression and HCC clinicopathologic parameters, we analyzed the liver hepatocellular carcinoma (LIHC) data in the TCGA database and found the levels of SH3PXD2B mRNA transcripts were positively associated with the pathological grades and TNM stages of HCC samples (both P < 0.05, Fig. 2a, b).