As a result (ORF1F2 = 2.56/2.58*2.92 = 0.34), the multiplicative interaction between TERT rs2736100 and TP53BP1 rs560191 in relation to lung cancer risk was statistically significant (OR for interaction = 0.34, 95% CI = 0.14–0.84). The gene discussed is TP53BP1; the disease is lung cancer.