Subjects with the GG genotype of OBFC1 rs11191865 and at least one C allele of TP53BP1 rs560191 (OR = 1.67, 95% CI = 0.93–2.99) presented a higher risk of lung cancer than those with at least one A allele of OBFC1 rs11191865 and at least one C allele of TP53BP1 rs560191 (OR = 1.37, 95% CI = 0.78–2.42), relative to the reference (subjects with at least one A allele of OBFC1 rs11191865 and the GG genotype of TP53BP1 rs560191). The gene discussed is TP53BP1; the disease is lung carcinoma.