Previously reported meta-analysis suggested that BAX -248 G>A and BCL2 -938 C>A are not directly associated with the overall cancer susceptibility but the correlation could be ethnicity-specific, which probably contributes to increasing adverse prognosis of cancer (Sahu et al., 2013; Zhang et al., 2014; Yao et al., 2017; Feng et al., 2018). The gene discussed is BCL2; the disease is cancer.