Some of these genes e.g. CHI3L1, ST6GALNAC5, COL11A1, MFAP5, TNFSF4 were identified also in our analysis as differentially expressed genes between ADC and control or between IPF and control suggesting that at least some disease related changes in the transcriptome are maintained during in vitro culture. Here, MFAP5 is linked to idiopathic pulmonary fibrosis.