TCF4 and Fanconi anemia: We did not observe overt differences in mutagenesis between fcd-2, fncm-1, or fnci-1 mutants, and wild-type, suggesting that the C. elegans Fanconi Anemia ICL repair pathway does not significantly contribute to the repair of DNA damage that occurs under normal, unchallenged growth conditions (Fig 2, S11A Fig).