FL-CNN and WL-CNN achieved AUC of 0.810 and 0.688 on the classification of grade (DLGG (grade II and grade III) vs. GBM (grade IV)), and 0.625 and 0.689 on the classification of Ki-67 level (< 10% vs. ≥ 10%), correspondingly. This evidence concerns the gene MKI67 and glioblastoma.