ACE2 and infection: In colon‐derived organoids, a small increase in ACE2 expression was observed at early times post‐infection (12 hpi) but at later time points (24 hpi) the overall expression of ACE2 (and other putative SARS‐CoV‐2 receptors and key cellular proteases) was decreased as compared to mock‐infected cells (Fig 3B).