HLA-G and cancer: HLA-G engages KIR2DL4 on dNK cells and LILRB1 on myeloid cells and some dNK cells, and may have the tolerogenic function.24 HLA-G may also help infected and cancer cells to escape immunosurveillance.25,26 Soluble HLA-G (sHLA-G) levels in the amniotic fluid of Toxoplasma gondii-infected pregnant women were greater in the group with congenital infection than in the group without vertical transmission.27 This illustrates the conflict of the maternal immune system between sustaining the growth of the fetus and protecting it from pathogens.