Studies have shown that an increased concentration of a highly sensitive C-reactive protein (hsCRP), which is a marker of the inflammatory response and a surrogate marker of IL-1 activity, in patients with acute coronary syndrome/myocardial infarction is independently associated with a risk of adverse cardiovascular outcomes in subsequent events (including HF) [6, 13, 19]. Here, IL1A is linked to myocardial infarction.