GH1 and depressive symptom measurement: The medical history included attention deficit hyperactivity disorder, gastrointestinal problems, anemia, and depression. The MRI was normal. The patient started GH treatment when they were 11 years old, height was − 2.8 SDS and their expected adult height was − 0.9 SDS. The GHD was diagnosed relatively late, which may have contributed to the other medical history. The patient self-administered the GH injections right from the start.