In investigating protein‒protein interactions with the STRING database among our prioritized candidate genes and other established candidates, interactions between genes with immune regulatory (but not with skin barrier) functions were found among the established AD players: TSLP and its receptor, TLR2, STAT6, IL4, and IFNGR. STRING data are not entirely comprehensive and omits other functional relationships between prioritized genes, described in Supplementary Results. The gene discussed is IL4; the disease is Alzheimer disease.