SFTPC and idiopathic pulmonary fibrosis: These Surfactant protein C (SPC)low ABCA3low KRT17pos KRT5neg intermediate cells exist in IPF lungs, consistent with the aberrant basaloid cells mentioned earlier (Adams et al., 2020; Habermann et al., 2020), implicating this organoid system mimics a gradual shift from hAEC2s to pathogenic IPF-like epithelium and thus may be a useful platform to study human epithelial metaplasia in IPF.