To get a broader perspective of whether the loss of Pelo impacts other aspects of translation more than the Hbs1l deficiency, we analyzed at first the translational efficiency (TE, Supplementary file 6) of genes by normalizing the abundance of ribosomal footprint reads to that of the RNA sequencing reads. The gene discussed is HBS1L; the disease is hyperinsulinemic hypoglycemia, familial, 4.