Another recent study performed on autopsy tissues from various organs observed that COVID-19 patients with coronary heart disease had upregulation of multiple protein belonging to RIG-I signaling pathway, and overall, interferon gamma receptor 1 (IFNGR1) was dysregulated in all the major organs except for the thyroid and testes (Nie et al., 2021). The gene discussed is RIGI; the disease is COVID-19.