In addition to MYC, increased levels of the H-Ras and K-Ras oncogenes were found in Friend’s murine erythroleukemia.65 Leder and co-workers established another series of transgenic mice in which the embryonic alpha-like zeta-globin gene was driving expression of an activated H-Ras oncogene. The gene discussed is HRAS; the disease is erythroleukemia.