Data from GEO (Balaguer et al., 2011; Pizzini et al., 2013; Martin et al., 2018) and TCGA (Muzny et al., 2012) suggested that colon cancer cells had lower miR-490-3p level and higher CDK1 level than normal colon mucosa cells (Figure 2B). Here, CDK1 is linked to malignant colon neoplasm.