2. De novo post-transplant associated TMA or secondary aHUS     a. Related to the type of donor and the organ procurement        - Complement activation associated to DBD and CDC        - Ischemia reperfusion injury     b. Associated to post-transplant events     - Drugs         - Calcineurin inhibitors        - mTOR inhibitors     - ABMR     - Infection     - Viral: CMV, parvovirus, Nile fever     - Funghi       Antiphospholipid syndrome     c. Other causes of TMA not related to the kidney transplant: malignancies, pregnancy, other drugs (anti VEGF, gemcitabine,...) The gene discussed is MTOR; the disease is antiphospholipid syndrome.