Univariate Cox regression results suggested that KANK2, MYO15A, SEMA3F, ATF7IP, CCNB1IP1, HNRNPC, PTGIR, ZNF85, PXDN, ZNF432, and LBH were closely related to the prognosis of glioblastoma. The gene discussed is PXDN; the disease is glioblastoma.