In this study hESF also had altered production of factors previously identified to be increased in the decidua of women with preeclampsia, including COL4A1 (Yong et al., 2014, 2015), LNPEP (Yong et al., 2014), TM9SF2 (Garrido-Gomez et al., 2017) and COTL1 (Garrido-Gomez et al., 2017). This evidence concerns the gene COL4A1 and preeclampsia.