Fragment AIFs include AFP-3BC, rAFP3D, and r3dAFP, which are fragments of protein derived from AFP domain-3, and they can deliver drugs and be endocytosed by cancer cells with high AFPR expression (Godovannyi et al., 2011; Posypanova et al., 2013; Yabbarov et al., 2013; Tcherkassova et al., 2017). This evidence concerns the gene AFP and cancer.