Alpha fetoprotein regulates the expression of oncogenes, inhibits apoptosis, promotes cancer cell growth, enhances drug resistance, enhances the antitumor immune response, increases invasion, and increases metastasis, resulting in the malignant transformation of cancer, and these functions of AFP are referred to as AFP malignant behaviors (Meng et al., 2016; Lu et al., 2016; Suryatenggara et al., 2017; Komorowski et al., 2018; Mizejewski, 2019; Xue et al., 2020). Here, AFP is linked to cancer.