However, the evidence demonstrated that the analyzed anxiety- and depression-related DEGs such as Gria1 (Rivera et al., 2020), Mapk1 (Sierra-Fonseca et al., 2019), Mapk9 (Thomson et al., 2020), and Fkbp5 (Zannas et al., 2019) contributed to anxiety or depression symptoms in rodents. Here, FKBP5 is linked to major depressive disorder.