Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling is critical to many aspects of tumor cell growth and survival (Porta et al., 2014) and therefore could be likely involved in the survival of irradiated cancer cells. The gene discussed is AKT1; the disease is neoplasm.