Upregulation of transgelin-2 expression is associated with metastasis and invasion of various cancer cells, including lung, bladder, colorectal, esophageal, and gastric cancers (Huang et al., 2008; Zhang et al., 2010; Chen et al., 2015; Du et al., 2016; Jin et al., 2016). The gene discussed is TAGLN2; the disease is cancer.