Transgelin-2 is also known to be phosphorylated at S83 and S163 residues via PFTK1, a cdc2-related serine/threonine protein kinase that has been shown to confer cell migratory properties in hepatocellular carcinoma (HCC) (Leung et al., 2011). This evidence concerns the gene CDK14 and hepatocellular carcinoma.