Moreover, the expression of apoptosis-related proteins, including cleaved caspase-3, cleaved PARP, and cleaved caspase substrate, as well as apoptosis rate, were increased when LINC02474 was depleted, suggesting that LINC02474 also affected the apoptosis of CRC cells (Figures 2D–G). Here, CASP3 is linked to colorectal carcinoma.