Thus far, erdafitinib and pemigatinib are the first FDA-approved FGFR selective inhibitors for treating urothelial cancer with FGFR2 or FGFR3 alterations, and cholangiocarcinoma with FGFR2 fusions and rearrangements, respectively (49–51). This evidence concerns the gene FGFR3 and cholangiocarcinoma.