PDLIM7 and nasopharyngeal carcinoma: Indeed, although most EBV strains characterized in the context of malignancy are predominantly B-lymphotropic (4–7), the few strains that have been studied in NPC have been found to harbor unique genetic polymorphisms in certain viral sequences (e.g., LMP1 and BZLF1 promoter) which endow them with greatly enhanced epitheliotropism (4, 8, 9).