YAP1 and neoplasm: Most recently, a combination of single cell analysis by SMART‐seq2 and 10 × Genomics scRNA‐seq validated tumor‐infiltrating immune cells and their cellular interactions for regulating tumor.[48] Another exciting study by single cell analysis of mouse and human CRCs also uncovered tumor initiating stem cells that display high YAP, regulated by signaling from a mesenchymal niche.[49] These findings further demonstrate the power of single cell analysis in the discovery of new cell types and their interactions and conversions.