The dormancy of CSCs or CSC‐like cells also have been found in other cancers, including breast melanoma, and glioblastoma.[58] We show that both dormant CSCs and proliferative EPCs highly express LGR5 and here link the dormant CSCs in CRC to proliferative EPCs as having been designated as TICs or tumor‐initiating stem cells.[59]. Here, LGR5 is linked to neoplasm.