MCL1 and esophageal squamous cell carcinoma: Next, to specify which part of the proapoptotic functions of OTUD1 contributes to the increased chemoresistance of ESCC cells after OTUD1 depletion, we xenografted parental, K244R, and K255R KYSE150 cells with or without OTUD1 knockout in nude mice then administered DDP alone or together with Z‐VAD or S63845 (an MCL1 inhibitor[37]).